Like other steroids, testosterone may be harmful in excess, especially when extra is taken without proper medical supervision; acne , highly oily skin, growth of some cancers, difficulty sleeping, and other complications are associated with abnormally high testosterone levels. However, a deficiency can also be harmful, and will have an impact on libido , energy, and maintenance of general health. Most human bodies are able to regulate hormone levels naturally, requiring no medical intervention. Some older men participate in androgen replacement therapy programs when their natural testosterone levels decline in order to maintain their younger state of health and vigor.
Research shows little evidence of abnormal or unhealthy psychological changes in men receiving supervised testosterone therapy to treat their low T, according to a study in the journal Therapeutics and Clinical Risk Management. However, mental and physical risks are involved in self-administration of artificial testosterone. Anyone abusing synthetic testosterone, also known as anabolic steroids, may experience episodes of aggressive or violent behavior, along with physical side effects. Bodybuilders, athletes, or anyone who seeks to build muscle mass or achieve other benefits from artificial testosterone should be aware of these risks.