Male hormone deficiency symptoms

Using appropriate tests for monitoring hormone therapy is crucial in establishing the appropriate dosing regimen. This reduces the chance of undesirable side effects and maximizes beneficial effects. For example, excessive use of androgens (testosterone, androstenedione, DHEA, and testosterone derivatives) can activate subclinical prostate tumors which are androgen-dependent. Monitoring is especially important in older males. By the age of 70, at least 50% of men have subclinical prostate cancer. These men are especially susceptible to prostate growth stimulation by androgens.

Infertility can result from a condition that is present at birth (congenital) or can develop later (acquired). Causes for infertility include the following:

  • Chemotherapy
  • Defect or obstruction in the reproductive system (., cryptorchidism, anorchism)
  • Disease (., cystic fibrosis, sickle cell anemia, sexually transmitted disease [STD])
  • Hormone dysfunction (caused by disorder in the hypothalamic-pituitary-gonadal axis)
  • Infection (., prostatitis, epididymitis, orchitis)
  • Injury (., testicular trauma)
  • Medications (., to treat high blood pressure, arthritis, etc.)
  • Metabolic disorders such as hemochromatosis (affects how the body uses and stores iron)
  • Retrograde ejaculation (., condition in which semen flows backwards into the bladder during ejaculation)
  • Systemic disease (., high fever, infection, kidney disease)
  • Testicular cancer
  • Varicocele

Information from the Nurses' Health Study indicated that the combination of estrogen and androgen used to treat hypoandrogenism could increase breast cancer risk. However, other studies indicated androgens may decrease breast cancer risk. Follow-up studies on the Women's Health Initiative found women who received estrogen and no progestogen showed a significant decrease in cardiovascular disease (CVD) and breast cancer. This has caused a reconsideration of androgens added to estrogens. Still, the FDA requires demonstration of CVD and breast cancer safety for any product containing androgens or estrogen plus an androgen; that has not been done.

Male hormone deficiency symptoms

male hormone deficiency symptoms


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