Liposomes are sub-microscopic bubbles made from phospholipids. Phospholipids surround every type of cell in the human body. When placed in liquid solutions phospholipids automatically form bubbles that encapsulate the host solution, thus protecting the substance from its surrounding environment. Scientists discovered that these tiny liposomes can be filled with nutrients in order to protect them during digestion and thus allow for increased bioavailability. Phospholipids are resistant to the digestive enzymes found in the gut that would normally be responsible for prematurely breaking down nutrients. They also pass through intestinal barriers with ease due to their small size. Some studies have shown that liposomal encapsulation can increase bioavailability by as much as 1500%.
Due to its chemical structure nandrolone is weakly exposed to aromatase (only 20% of the aromatizing activity of testosterone). However, not estrogenic effects are its main concern: nandrolone has a potent progestogenic activity (20% of progesterone). While binding to progestogenic pituitary receptors nandrolone causes increased production of prolactin, which in effect is very similar to estrogen: its effect presents in reducing testosterone production, increasing fat mass and in gynecomastia. To prevent these side effects prolactin inhibitors (cabergoline) shall always be at hand when on nandrolones cycle.